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POIRIER LAB

 

RESEARCH

Current Areas of Study

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DNA
Embryonic Stem Cells

RNA VIRUS HOST FACTORS

We discover and catalog the host proteins that RNA viruses hijack to complete their life cycles, defining the landscape of potential therapeutic targets. Current research focuses on coronaviruses.

GENOME ENGINEERING TECHNOLOGIES

We develop genome engineering technologies that enable parallel orchestration of large numbers of genetic variants in a single experiment in order to study their function.

MODULATORS OF REPLICATION STRESS

We seek to understand the mechanistic basis underlying how normal and cancer cells differ in their ability to cope with replication stress induced by DNA damaging chemotherapy.

CANCER SELECTIVE CELL SURFACE TARGETS

We identify cancer selective cell surface proteins through an integrated target discovery pipeline and develop molecular probes suitable for diagnostic and therapeutic applications.